Brugada syndrome panel

Genes: 

Sinonimo: 

Bangungut;;Dream disease;;Idiopathic ventricular fibrillation, Brugada type;;Pokkuri death syndrome;SUNDS;;Sudden unexplained nocturnal death syndrome

Tipo de test: 

Tiempo de espera: 

0 dias

Más información

Brugada syndrome is an inherited disorder characterized by an electrocardiographic (EEC) pattern: ST segment elevation in the right precordial EEC (type 1), incomplete or complete blockage of the right branch and negative T wave; well as a high incidence of sudden death in patients with normal heart.
Brugada syndrome can be caused by mutations in eight different genes (SCN5A, GPD1L, CACNA1C, CACNB2, SCN1B, KCNE3, SCN3B, and HCN4) and it presents a pattern of autosomal dominant inheritance, so that children from sick parents have a 50% chance of developing the disease.
The syndrome is typically manifested in adulthood, and the mean age of sudden death ranges from 15 to 40 years. Also it may occur in infants and children.
It is difficult to accurately estimate the prevalence of the syndrome, however the data suggest that Brugada syndrome occur in populations around the world, where the prevalence would reach values ​​of the order of 1:2000 people in endemic regions.
You can learn more about the different types of Brugada syndrome accessing its section.

Fuente: 

Tomado de GeneReviews

Prevalencia: 

1/2000

Herencia: 

Autosomal dominant